V de Franciscis Selected Research

Proto-Oncogene Proteins c-ret

10/2003	The tyrosine phosphatase Shp-2 mediates intracellular signaling initiated by Ret mutants.
6/2000	Abrogation of nerve growth factor-induced terminal differentiation by ret oncogene involves perturbation of nuclear translocation of ERK.
6/2000	Signaling through Ras is essential for ret oncogene-induced cell differentiation in PC12 cells.

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V de Franciscis Research Topics

Disease

6	Neoplasms (Cancer) 01/2013 - 03/2000
3	Pheochromocytoma 06/2000 - 03/2000
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2013
1	Lung Neoplasms (Lung Cancer) 01/2013
1	Glioma (Gliomas) 01/2012
1	Thyroid Neoplasms (Thyroid Cancer) 07/2000
1	Multiple Endocrine Neoplasia (Multiple Endocrine Adenomatosis) 06/2000
1	Familial medullary thyroid carcinoma 06/2000
1	Multiple Endocrine Neoplasia Type 2a (MEN 2) 06/2000
1	Multiple Endocrine Neoplasia Type 2b (MEN 3) 06/2000

Drug/Important Bio-Agent (IBA)

3	Proto-Oncogene Proteins c-retIBA 10/2003 - 06/2000
2	RNA (Ribonucleic Acid)IBA 01/2011 - 07/2000
2	Proteins (Proteins, Gene)FDA Link 10/2003 - 03/2000
1	AP20187IBA 01/2013
1	Pharmaceutical PreparationsIBA 01/2013
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2013
1	MicroRNAs (MicroRNA)IBA 01/2013
1	Caspase 8 (Caspase-8)IBA 01/2013
1	OligonucleotidesIBA 01/2012
1	Nucleic AcidsIBA 01/2012
1	Phosphotransferases (Kinase)IBA 01/2011
1	LigandsIBA 01/2011
1	EpitopesIBA 01/2011
1	Monoclonal AntibodiesIBA 01/2011
1	DNA (Deoxyribonucleic Acid)IBA 01/2011
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 10/2003
1	Ribonucleases (Ribonuclease)IBA 07/2000
1	Nerve Growth Factor (NGF)IBA 06/2000
1	Protein Isoforms (Isoforms)IBA 05/2000
1	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 03/2000
1	PhosphotyrosineIBA 03/2000

Therapy/Procedure

1	Therapeutics 01/2011